VPS37C

Across TCGA patient cohorts, VPS37C RNA expression is significantly associated with the go_rna of many other GO terms, with 7,165 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible VPS37C-associated GO terms across cancer lineages are Hippo signaling, DNA-templated transcription initiation, and Transcription preinitiation complex assembly. Each is linked with VPS37C in more than 25 cancer types. Because this analysis shows association rather than direction, both VPS37C-to-partner and partner-to-VPS37C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hippo signaling grouped by VPS37C-low versus VPS37C-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS37C→partner) and Y-score (partner→VPS37C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Hippo signaling →	+0.060	+0.722	.001	<.001	3	26
LIHC	DNA-templated transcription initiation →	+0.037	+0.805	<.001	<.001	3	26
ACC	Transcription preinitiation complex assembly →	+0.044	+1.040	<.001	<.001	3	26
DLBC	Negative regulation of macroautophagy →	+0.073	+0.768	.001	<.001	3	25
DLBC	Vesicle-mediated transport between endosomal compartments →	+0.079	+1.066	.006	<.001	2	26
THYM	Golgi localization →	+0.067	+0.841	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,165 associations by consensus.

Hippo signaling by VPS37C expression — DLBC

Explore this box plot interactively →