VPS37C

Across TCGA patient cohorts, VPS37C protein abundance is significantly associated with the RNA expression of many other genes, with 7,888 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible VPS37C-associated genes across cancer lineages are SCUBE2, C14orf132, and HACD1. Each is linked with VPS37C in more than 3 cancer types. Because this analysis shows association rather than direction, both VPS37C-to-partner and partner-to-VPS37C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS37C versus SCUBE2 in BRCA, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS37C→partner) and Y-score (partner→VPS37C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SCUBE2 →	+2.130	+0.338	<.001	<.001	3	4
UCEC	C14orf132 →	+1.231	+0.303	.004	.001	3	4
BRCA	HACD1 →	-0.767	-0.410	.002	<.001	3	3
OV	TSG101 →	+0.446	+0.245	<.001	.004	3	3
COAD	CASQ2 →	+1.189	+0.254	.005	.007	3	3
BRCA	NCAPH →	-0.797	-0.392	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,888 associations by consensus.

VPS37C vs SCUBE2 — BRCA

Explore this scatter interactively →