VPS37C

Across TCGA cell cohorts, VPS37C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,845 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VPS37C-associated GO terms across cancer lineages are Endosomal transport, Late endosome to vacuole transport, and Cytosolic transport. Each is linked with VPS37C in more than 13 cancer types. Because this analysis shows association rather than direction, both VPS37C-to-partner and partner-to-VPS37C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by VPS37C-low versus VPS37C-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS37C→partner) and Y-score (partner→VPS37C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.058	+0.780	<.001	<.001	3	14
LUNG_SCLC	Late endosome to vacuole transport →	+0.085	+0.576	<.001	<.001	3	14
SOFT_TISSUE	Cytosolic transport →	+0.073	+0.777	<.001	<.001	3	13
LARGE_INTESTINE	mRNA alternative polyadenylation →	+0.091	+0.798	<.001	<.001	3	12
LARGE_INTESTINE	Negative regulation of DNA-templated transcription initiation →	+0.135	+0.690	<.001	.005	3	12
LARGE_INTESTINE	Negative regulation of transcription initiation by RNA polymerase II →	+0.135	+0.690	<.001	.005	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,845 associations by consensus.

Endosomal transport by VPS37C expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →