VPS37C

Across TCGA cell cohorts, VPS37C protein abundance is significantly associated with the RNA expression of many other genes, with 3,981 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VPS37C-associated genes across cancer lineages are ZNF668, MLKL, and PIGW. Each is linked with VPS37C in more than 4 cancer types. Because this analysis shows association rather than direction, both VPS37C-to-partner and partner-to-VPS37C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS37C versus ZNF668 in CNS, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS37C→partner) and Y-score (partner→VPS37C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ZNF668 →	+0.742	+1.669	.001	.003	3	5
LUNG_SCLC	MLKL →	-1.394	-1.038	.004	.009	3	5
LUNG_SCLC	PIGW →	+0.649	+1.235	<.001	.001	3	5
BONE	SLC38A2 →	+0.834	+1.081	.006	.001	3	4
SKIN	MAD2L2 →	+0.700	+1.052	.009	.005	3	4
SKIN	AP3D1 →	+0.854	+1.176	.007	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,981 associations by consensus.

VPS37C vs ZNF668 — CNS

Explore this scatter interactively →