VPS37C

Across TCGA cell cohorts, VPS37C mutation is significantly associated with the mutation status of many other genes, with 858 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VPS37C-associated genes across cancer lineages are MED23, GUSB, and OR5T3. Each is linked with VPS37C in more than 1 cancer types. Because this analysis shows association rather than direction, both VPS37C-to-partner and partner-to-VPS37C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MED23 grouped by VPS37C-low versus VPS37C-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS37C→partner) and Y-score (partner→VPS37C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MED23 →	+4.000	+5.050	.008	.008	1	2
LARGE_INTESTINE	GUSB →	+4.087	+5.044	.001	.001	1	2
LARGE_INTESTINE	OR5T3 →	+4.087	+5.044	.001	.001	1	2
LARGE_INTESTINE	GOLIM4 →	+3.350	+4.584	.003	.003	1	2
LARGE_INTESTINE	FOSL1 →	+5.087	+4.523	.006	.006	1	2
LARGE_INTESTINE	OR51B4 →	+3.672	+4.799	.002	.002	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 858 associations by consensus.

MED23 by VPS37C expression — BLOOD_Leukemia

Explore this box plot interactively →