VPS37B

Across TCGA patient cohorts, VPS37B protein abundance is significantly associated with the RNA expression of many other genes, with 12,864 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible VPS37B-associated genes across cancer lineages are ANXA3, MPP1, and CYP7B1. Each is linked with VPS37B in more than 4 cancer types. Because this analysis shows association rather than direction, both VPS37B-to-partner and partner-to-VPS37B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS37B versus ANXA3 in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS37B→partner) and Y-score (partner→VPS37B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ANXA3 →	+1.153	+0.233	.001	.008	3	5
COAD	MPP1 →	-1.232	-0.336	<.001	<.001	3	4
GBM	CYP7B1 →	-0.944	-0.289	.001	.002	3	4
GBM	ACSM5 →	-1.043	-0.320	<.001	.001	3	4
GBM	SOX9 →	+0.955	+0.369	<.001	<.001	3	4
BRCA	SGK3 →	-0.742	-0.219	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,864 associations by consensus.

VPS37B vs ANXA3 — BRCA

Explore this scatter interactively →