VPS37B

Across TCGA cell cohorts, VPS37B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,996 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible VPS37B-associated GO terms across cancer lineages are Regulation of viral budding via host ESCRT complex, Positive regulation of viral budding via host ESCRT complex, and Viral budding via host ESCRT complex. Each is linked with VPS37B in more than 18 cancer types. Because this analysis shows association rather than direction, both VPS37B-to-partner and partner-to-VPS37B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of viral budding via host ESCRT complex grouped by VPS37B-low versus VPS37B-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS37B→partner) and Y-score (partner→VPS37B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of viral budding via host ESCRT complex →	+0.174	+1.283	<.001	<.001	3	19
SOFT_TISSUE	Positive regulation of viral budding via host ESCRT complex →	+0.174	+1.283	<.001	<.001	3	19
URINARY_TRACT	Viral budding via host ESCRT complex →	+0.120	+0.945	.001	.003	3	15
LIVER	Viral release from host cell →	+0.109	+0.922	.001	.001	2	14
LIVER	Exit from host cell →	+0.109	+0.922	.001	.001	2	14
LUNG_NSCLC_LUSC	Viral budding →	+0.106	+1.188	.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,996 associations by consensus.

Regulation of viral budding via host ESCRT complex by VPS37B expression — SOFT_TISSUE

Explore this box plot interactively →