VPS36

Across TCGA cell cohorts, VPS36 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,376 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VPS36-associated GO terms across cancer lineages are Retrograde transport, vesicle recycling within Golgi, Copper ion export, and Intra-Golgi vesicle-mediated transport. Each is linked with VPS36 in more than 13 cancer types. Because this analysis shows association rather than direction, both VPS36-to-partner and partner-to-VPS36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde transport, vesicle recycling within Golgi grouped by VPS36-low versus VPS36-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS36→partner) and Y-score (partner→VPS36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Retrograde transport, vesicle recycling within Golgi →	+0.121	+1.040	<.001	<.001	3	14
BLOOD_Myeloma	Copper ion export →	-0.195	-0.799	<.001	<.001	3	14
STOMACH	Intra-Golgi vesicle-mediated transport →	+0.113	+1.200	<.001	<.001	3	12
BLOOD_Lymphoma	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.105	+0.661	<.001	<.001	3	12
PANCREAS	Post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.097	+0.892	<.001	<.001	3	11
LARGE_INTESTINE	Ornithine transport →	+0.185	+0.605	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,376 associations by consensus.

Retrograde transport, vesicle recycling within Golgi by VPS36 expression — STOMACH

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