VPS35L

Across TCGA patient cohorts, VPS35L RNA expression is significantly associated with the protein abundance of many other proteins, with 9,772 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible VPS35L-associated proteins across cancer lineages are FTO, SEC63, and HSPA12B_S434. Each is linked with VPS35L in more than 4 cancer types. Because this analysis shows association rather than direction, both VPS35L-to-partner and partner-to-VPS35L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS35L versus FTO in CCRCC, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS35L→partner) and Y-score (partner→VPS35L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FTO →	+0.249	+0.244	<.001	.003	3	5
UCEC	SEC63 →	-0.459	-0.447	.002	.002	3	4
BRCA	HSPA12B_S434 →	+0.677	+0.575	<.001	<.001	3	4
BRCA	THUMPD1 →	+0.373	+0.495	<.001	<.001	3	4
CCRCC	RPL6 →	-0.508	-0.440	<.001	<.001	3	4
BRCA	DDX18 →	-0.402	-0.558	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,772 associations by consensus.

VPS35L vs FTO — CCRCC

Explore this scatter interactively →