VPS35L

Across TCGA cell cohorts, VPS35L RNA expression is significantly associated with the go_rna of many other GO terms, with 2,963 significant associations in total. BONE shows the largest number of these associations.

The most reproducible VPS35L-associated GO terms across cancer lineages are Golgi vesicle transport, Vacuole organization, and Platelet aggregation. Each is linked with VPS35L in more than 11 cancer types. Because this analysis shows association rather than direction, both VPS35L-to-partner and partner-to-VPS35L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by VPS35L-low versus VPS35L-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS35L→partner) and Y-score (partner→VPS35L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Golgi vesicle transport →	+0.041	+0.684	.002	.009	3	12
BONE	Vacuole organization →	+0.054	+1.659	.002	.001	3	9
BREAST	Platelet aggregation →	+0.082	+1.238	.007	.003	3	9
LARGE_INTESTINE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.048	+1.222	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Host-mediated perturbation of viral process →	+0.046	+1.101	.001	.004	3	9
LUNG_SCLC	Vesicle budding from membrane →	+0.065	+0.685	.003	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,963 associations by consensus.

Golgi vesicle transport by VPS35L expression — CNS

Explore this box plot interactively →