Across TCGA patient cohorts, VPS33B protein abundance is significantly associated with the RNA expression of many other genes, with 3,259 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible VPS33B-associated genes across cancer lineages are TMEM17, PLPP7, and PGAP4. Each is linked with VPS33B in more than 2 cancer types. Because this analysis shows association rather than direction, both VPS33B-to-partner and partner-to-VPS33B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS33B→partner) and Y-score (partner→VPS33B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TMEM17 →	-0.789	-0.244	<.001	<.001	3	3
BRCA	PLPP7 →	+0.474	+0.257	.001	<.001	3	2
LUAD	PGAP4 →	+0.896	+0.222	<.001	.004	3	2
LUAD	TBC1D2B →	+0.451	+0.270	<.001	<.001	3	2
BRCA	CCDC8 →	+0.898	+0.235	<.001	.001	3	2
BRCA	TOR4A →	+0.587	+0.318	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,259 associations by consensus.

Exploration

VPS33B survival (RNA) · tumor vs normal (RNA) · all VPS33B data types