VPS29

Across TCGA pan-cancer cohorts, VPS29 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated VPS29 data layer compared with 22 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher VPS29 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated VPS29 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LSCC show a favorable association.

PDAC, CCRCC, and LSCC are the cancer types where VPS29 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.484	0.286	.004	11	view →
CCRCC	DFS	Quartile	All	0.585	0.833	.020	4	view →
LSCC	DFS	Quartile	All	0.784	0.203	.010	3	view →
HNSC	DFS	Tertile	III,IV	0.879	0.675	.033	3	view →
GBM	OS	Median	All	0.853	0.775	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

VPS29–PDAC (OS)

Open the PDAC breakdown →