Across TCGA pan-cancer cohorts, VPS26BP1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated VPS26BP1 data layer.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher VPS26BP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated VPS26BP1 expression acts as an unfavorable survival marker, although some lineages such as LAML and ESCA show a favorable association.
ACC, LAML, and THYM are the cancer types where VPS26BP1 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.