Across TCGA pan-cancer cohorts, VPS25P1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of VPS25P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where VPS25P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types VPS25P1 is over-expressed in tumor.

KIRC, KICH, and LUSC are the cancer types where VPS25P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in VPS25P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.043	.003	5	view →
KICH	Male	II,III,IV	+0.053	.044	1	view →
LUSC	All	All	+0.049	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: VPS25P1 RNA expression & survival · all VPS25P1 data types