Across TCGA patient cohorts, VPS16 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,753 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VPS16-associated proteins across cancer lineages are NSFL1C, CRNKL1, and XRN2. Each is linked with VPS16 in more than 6 cancer types. Because this analysis shows association rather than direction, both VPS16-to-partner and partner-to-VPS16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS16→partner) and Y-score (partner→VPS16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NSFL1C →	+0.435	+0.648	<.001	<.001	3	7
GBM	CRNKL1 →	+0.336	+0.406	<.001	<.001	3	6
GBM	XRN2 →	+0.282	+0.369	<.001	<.001	3	5
OV	RBBP9 →	+0.453	+0.641	.001	<.001	3	5
OV	TRMT6 →	+0.414	+0.831	<.001	<.001	3	5
OV	TRMT61A →	+0.328	+0.674	.003	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,753 associations by consensus.

Exploration

VPS16 survival (RNA) · tumor vs normal (RNA) · all VPS16 data types