Across TCGA cell cohorts, VPS16 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,840 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible VPS16-associated GO terms across cancer lineages are Regulation of protein localization to endoplasmic reticulum, Positive regulation of protein localization to endoplasmic reticulum, and Regulation of peroxisome organization. Each is linked with VPS16 in more than 15 cancer types. Because this analysis shows association rather than direction, both VPS16-to-partner and partner-to-VPS16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS16→partner) and Y-score (partner→VPS16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of protein localization to endoplasmic reticulum →	+0.133	+0.649	.002	<.001	3	16
CNS	Positive regulation of protein localization to endoplasmic reticulum →	+0.146	+0.786	<.001	<.001	3	15
LARGE_INTESTINE	Regulation of peroxisome organization →	+0.215	+0.972	<.001	<.001	3	11
CNS	Regulation by virus of viral protein levels in host cell →	+0.142	+0.578	<.001	.001	3	11
LUNG_NSCLC_LUSC	Vacuole fusion →	+0.146	+1.250	.002	<.001	3	11
URINARY_TRACT	Lysosome organization →	+0.055	+0.857	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,840 associations by consensus.

Exploration

VPS16 survival (RNA) · tumor vs normal (RNA) · all VPS16 data types