VPS13D

Across TCGA patient cohorts, VPS13D RNA expression is significantly associated with the protein abundance of many other proteins, with 13,759 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible VPS13D-associated proteins across cancer lineages are DDAH1, EIF2S2, and EIF5B_S1168. Each is linked with VPS13D in more than 4 cancer types. Because this analysis shows association rather than direction, both VPS13D-to-partner and partner-to-VPS13D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VPS13D versus DDAH1 in UCEC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS13D→partner) and Y-score (partner→VPS13D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DDAH1 →	+0.545	+0.475	.001	.002	3	5
BRCA	EIF2S2 →	-0.220	-0.614	<.001	<.001	3	5
BRCA	EIF5B_S1168 →	-0.432	-0.468	<.001	<.001	3	5
GBM	FNDC3B →	-0.522	-0.495	<.001	<.001	3	5
BRCA	RPL4 →	-0.381	-0.603	<.001	<.001	3	5
GBM	SND1 →	-0.275	-0.368	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,759 associations by consensus.

VPS13D vs DDAH1 — UCEC

Explore this scatter interactively →