VPS13D

Across TCGA cell cohorts, VPS13D RNA expression is significantly associated with the go_rna of many other GO terms, with 3,877 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VPS13D-associated GO terms across cancer lineages are Vacuolar transport, Negative regulation of autophagy, and Golgi vesicle transport. Each is linked with VPS13D in more than 17 cancer types. Because this analysis shows association rather than direction, both VPS13D-to-partner and partner-to-VPS13D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuolar transport grouped by VPS13D-low versus VPS13D-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VPS13D→partner) and Y-score (partner→VPS13D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Vacuolar transport →	+0.070	+0.669	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Negative regulation of autophagy →	+0.091	+1.029	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.067	+0.966	.003	<.001	2	18
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.077	+0.956	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitophagy →	+0.138	+1.196	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Process utilizing autophagic mechanism →	+0.074	+0.856	<.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,877 associations by consensus.

Vacuolar transport by VPS13D expression — LUNG_SCLC

Explore this box plot interactively →