VOPP1

Across TCGA pan-cancer cohorts, VOPP1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated VOPP1 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher VOPP1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated VOPP1 expression acts as an unfavorable survival marker.

LIHC, COAD, and LUSC are the cancer types where VOPP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.010	0.784	<.001	24	view →
COAD	OS	Median	All	0.001	0.871	<.001	18	view →
LUSC	DFS	Median	III,IV	0.079	0.658	<.001	16	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	DFS	Median	III,IV	0.058	0.648	.001	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

VOPP1–LIHC (OS)

Open the LIHC breakdown →