VOPP1

Across TCGA cell cohorts, VOPP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,617 significant associations in total. CNS shows the largest number of these associations.

The most reproducible VOPP1-associated GO terms across cancer lineages are Integrin-mediated signaling pathway, Regulation of angiotensin-activated signaling pathway, and Endoplasmic reticulum localization. Each is linked with VOPP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both VOPP1-to-partner and partner-to-VOPP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Integrin-mediated signaling pathway grouped by VOPP1-low versus VOPP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VOPP1→partner) and Y-score (partner→VOPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Integrin-mediated signaling pathway →	+0.272	+1.341	<.001	<.001	3	11
BONE	Regulation of angiotensin-activated signaling pathway →	+0.232	+0.889	.001	.006	3	11
BONE	Endoplasmic reticulum localization →	+0.144	+0.944	.002	.001	3	11
BONE	Actin filament organization →	+0.152	+1.178	<.001	<.001	3	10
BONE	Cellular response to abiotic stimulus →	+0.053	+1.308	.001	<.001	3	10
BONE	Cellular response to environmental stimulus →	+0.053	+1.308	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,617 associations by consensus.

Integrin-mediated signaling pathway by VOPP1 expression — BONE

Explore this box plot interactively →