Across TCGA pan-cancer cohorts, VN1R7P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of VN1R7P’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where VN1R7P RNA is repressed in tumor relative to normal tissue. In most cancer types VN1R7P is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
BRCA and UCEC are the cancer types where VN1R7P tumor–normal differential expression is most reproducible.