VN1R74P

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, VN1R74P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,238 significant associations in total. STAD shows the largest number of these associations.

The most reproducible VN1R74P-associated GO terms across cancer lineages are Insulin receptor signaling pathway, Regulation of membrane permeability, and Regulation of mitochondrion organization. Each is linked with VN1R74P in more than 7 cancer types. Because this analysis shows association rather than direction, both VN1R74P-to-partner and partner-to-VN1R74P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Insulin receptor signaling pathway grouped by VN1R74P-low versus VN1R74P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VN1R74P→partner) and Y-score (partner→VN1R74P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADInsulin receptor signaling pathway →+0.074+0.171<.001<.00138
STADRegulation of membrane permeability →+0.084+0.184<.001<.00138
STADRegulation of mitochondrion organization →+0.082+0.194<.001<.00138
ESCAObsolete positive regulation of mitochondrion organization →+0.076+0.146<.001.00238
STADCellular response to decreased oxygen levels →+0.075+0.212<.001<.00138
STADPeptidyl-lysine methylation →+0.072+0.207<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,238 associations by consensus.

Insulin receptor signaling pathway by VN1R74P expression — STAD

Box plot of Insulin receptor signaling pathway in VN1R74P-low vs VN1R74P-high samples in STAD.

Explore this box plot interactively →

Exploration