VN1R53P

Across TCGA pan-cancer cohorts, VN1R53P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated VN1R53P data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher VN1R53P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated VN1R53P expression acts as an unfavorable survival marker, although some lineages such as BRCA show a favorable association.

TGCT, KIRC, and BRCA are the cancer types where VN1R53P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	III,IV	0.003	1.000	<.001	96	view →
KIRC	DFS	Tertile	IV	0.326	0.659	.002	96	view →
BRCA	OS	Tertile	All	0.980	0.944	<.001	66	view →
LIHC	OS	Tertile	All	0.374	0.725	<.001	60	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
THCA	DFS	Tertile	IV	0.126	0.805	.002	21	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
KICH	DFS	Median	All	0.707	0.923	.017	4	view →
SKCM	OS	Tertile	All	0.655	0.794	.034	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

VN1R53P–TGCT (OS)

Open the TGCT breakdown →