Across TCGA patient cohorts, VN1R5 mutation is significantly associated with the RNA expression of many other genes, with 1,124 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible VN1R5-associated genes across cancer lineages are NDUFAF5, SEC13, and CIAO2B. Each is linked with VN1R5 in more than 2 cancer types. Because this analysis shows association rather than direction, both VN1R5-to-partner and partner-to-VN1R5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VN1R5→partner) and Y-score (partner→VN1R5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NDUFAF5 →	+0.702	+3.328	<.001	.005	3	3
UCEC	SEC13 →	+0.654	+3.807	<.001	<.001	3	2
UCEC	CIAO2B →	+0.522	+3.483	.001	.002	3	2
UCEC	UBXN6 →	+0.424	+3.828	.004	<.001	3	2
UCEC	E4F1 →	+0.454	+3.259	.001	.008	3	2
UCEC	CENPX →	+0.689	+3.491	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,124 associations by consensus.

Exploration

VN1R5 survival (RNA) · tumor vs normal (RNA) · all VN1R5 data types