Across TCGA patient cohorts, VN1R5 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VN1R5-associated genes across cancer lineages are Annexin-1, Cyclin-B1, and Heregulin. Each is linked with VN1R5 in more than 1 cancer types. Because this analysis shows association rather than direction, both VN1R5-to-partner and partner-to-VN1R5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VN1R5→partner) and Y-score (partner→VN1R5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.823	+2.189	.001	.034	3	1
UCEC	Cyclin-B1 →	+0.737	+3.459	.008	.005	3	1
UCEC	Heregulin →	-0.125	-2.321	.043	.035	2	1
UCEC	Caspase-8 →	-0.318	-3.169	.011	.019	2	1
UCEC	p62 Lck ligand →	+0.387	+2.321	.017	.035	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

VN1R5 survival (RNA) · tumor vs normal (RNA) · all VN1R5 data types