Across TCGA pan-cancer cohorts, VN1R40P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of VN1R40P’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where VN1R40P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types VN1R40P is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.
LUAD and COAD are the cancer types where VN1R40P tumor–normal differential expression is most reproducible.