Across TCGA pan-cancer cohorts, VN1R21P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of VN1R21P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where VN1R21P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types VN1R21P is over-expressed in tumor, although a few such as PRAD and THCA show the opposite, repressed pattern.

LUSC, PRAD, and LUAD are the cancer types where VN1R21P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in VN1R21P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+0.136	<.001	7	view →
PRAD	All	All	−0.033	.048	2	view →
LUAD	All	All	+0.014	.040	2	view →
THCA	Male	All	−0.031	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: VN1R21P RNA expression & survival · all VN1R21P data types