Across TCGA pan-cancer cohorts, VN1R11P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of VN1R11P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where VN1R11P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types VN1R11P is over-expressed in tumor.
KIRC, BRCA, and PRAD are the cancer types where VN1R11P tumor–normal differential expression is most reproducible.