VN1R108P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, VN1R108P RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of VN1R108P’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where VN1R108P RNA is repressed in tumor relative to normal tissue. In most cancer types VN1R108P is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, BRCA, and KIRC are the cancer types where VN1R108P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in VN1R108P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
THCAMaleAll−0.858<.0019view →
BRCAFemaleAll−0.390<.0016view →
KIRCAllII,III,IV−0.309.0036view →
LIHCAllAll+0.164<.0015view →
KIRPAllIV+0.937<.0014view →
CHOLAllAll+0.848<.0014view →
BLCAFemaleAll+0.470.0333view →
PAADFemaleAll+0.640.0092view →
KICHAllAll−0.551.0042view →
UCECAllAll−0.341.0422view →
COADMaleAll+0.303.0202view →
LUADAllIII,IV−0.291.0431view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

VN1R108P–THCA

Tumor-vs-normal expression box plot for VN1R108P RNA in THCA.

Open the THCA breakdown →

Exploration