VN1R1

Across TCGA cell cohorts, VN1R1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,229 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible VN1R1-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Protein localization to cytoplasmic stress granule. Each is linked with VN1R1 in more than 14 cancer types. Because this analysis shows association rather than direction, both VN1R1-to-partner and partner-to-VN1R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by VN1R1-low versus VN1R1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VN1R1→partner) and Y-score (partner→VN1R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.126	+0.437	<.001	<.001	3	15
OVARY	Negative regulation of myoblast fusion →	+0.130	+0.577	<.001	<.001	3	14
STOMACH	Protein localization to cytoplasmic stress granule →	+0.145	+0.872	.001	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Stress granule assembly →	+0.113	+0.356	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of RNA splicing →	+0.090	+0.522	<.001	<.001	3	14
OVARY	Regulation of mRNA splicing, via spliceosome →	+0.082	+0.454	<.001	.004	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,229 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by VN1R1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →