VMP1

Across TCGA pan-cancer cohorts, VMP1 mass-spec protein differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of VMP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where VMP1 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types VMP1 is over-expressed in tumor.

LUAD, LSCC, and COAD are the cancer types where VMP1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in VMP1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	+0.550	<.001	9	view →
LSCC	Male	All	+0.512	<.001	9	view →
COAD	Female	II,III,IV	+0.240	<.001	9	view →
HNSC	All	III,IV	+0.443	<.001	8	view →
CCRCC	All	II,III,IV	+0.194	.002	5	view →
PDAC	Female	II,III,IV	+0.809	.003	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

VMP1–LUAD

Open the LUAD breakdown →