VMO1

Across TCGA cell cohorts, VMO1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible VMO1-associated genes across cancer lineages are OR10C1, CCDC63, and OR5V1. Each is linked with VMO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both VMO1-to-partner and partner-to-VMO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10C1 grouped by VMO1-low versus VMO1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VMO1→partner) and Y-score (partner→VMO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR10C1 →	+0.043	+5.029	<.001	.006	3	1
LARGE_INTESTINE	CCDC63 →	+0.055	+3.920	<.001	.005	3	1
LARGE_INTESTINE	OR5V1 →	+0.008	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR10C1 by VMO1 expression — LUNG_SCLC

Explore this box plot interactively →