Across TCGA patient cohorts, VMAC RNA expression is significantly associated with the protein abundance of many other proteins, with 15,888 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible VMAC-associated proteins across cancer lineages are LARP4, RPL5, and DDX21_S89. Each is linked with VMAC in more than 5 cancer types. Because this analysis shows association rather than direction, both VMAC-to-partner and partner-to-VMAC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VMAC→partner) and Y-score (partner→VMAC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LARP4 →	-0.278	-0.278	<.001	<.001	3	6
LUAD	RPL5 →	-0.244	-0.484	<.001	<.001	3	5
LUAD	DDX21_S89 →	-0.868	-0.289	<.001	.001	3	5
LUAD	ERO1A →	-0.463	-0.290	<.001	<.001	3	5
PDAC	LMNB2 →	+0.268	+0.318	.005	.004	2	6
BRCA	PEBP1 →	+0.381	+0.431	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,888 associations by consensus.

Exploration

VMAC survival (RNA) · tumor vs normal (RNA) · all VMAC data types