Across TCGA patient cohorts, VMAC protein abundance is significantly associated with the RNA expression of many other genes, with 7,653 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible VMAC-associated genes across cancer lineages are TACC3, UBE2C, and SEPTIN14P12. Each is linked with VMAC in more than 2 cancer types. Because this analysis shows association rather than direction, both VMAC-to-partner and partner-to-VMAC results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VMAC→partner) and Y-score (partner→VMAC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TACC3 →	-0.961	-0.594	<.001	<.001	3	3
BRCA	UBE2C →	-1.186	-0.501	<.001	<.001	3	3
LUAD	SEPTIN14P12 →	-0.654	-0.362	<.001	<.001	3	3
UCEC	CCNE1 →	-1.534	-0.574	.001	.001	3	3
BRCA	E2F3 →	-0.692	-0.464	.001	.002	3	3
UCEC	MTFR2 →	-0.831	-0.498	.004	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,653 associations by consensus.

Exploration

VMAC survival (RNA) · tumor vs normal (RNA) · all VMAC data types