Across TCGA patient cohorts, VKORC1L1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,561 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VKORC1L1-associated proteins across cancer lineages are PUS7, SBDS, and GTF2I. Each is linked with VKORC1L1 in more than 6 cancer types. Because this analysis shows association rather than direction, both VKORC1L1-to-partner and partner-to-VKORC1L1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VKORC1L1→partner) and Y-score (partner→VKORC1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PUS7 →	+0.523	+0.604	<.001	<.001	3	7
GBM	SBDS →	+0.328	+0.376	<.001	<.001	3	7
LSCC	GTF2I →	+0.483	+0.631	<.001	<.001	3	7
GBM	TRIM24 →	+0.536	+0.528	<.001	<.001	3	6
HNSC	PSMB10 →	-0.618	-0.586	<.001	<.001	3	5
GBM	PURB →	+0.307	+0.397	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,561 associations by consensus.

Exploration

VKORC1L1 survival (RNA) · tumor vs normal (RNA) · all VKORC1L1 data types