VKORC1

Across TCGA patient cohorts, VKORC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,419 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible VKORC1-associated proteins across cancer lineages are FKBP10, IKBIP, and P4HA1. Each is linked with VKORC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both VKORC1-to-partner and partner-to-VKORC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VKORC1 versus FKBP10 in LSCC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VKORC1→partner) and Y-score (partner→VKORC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FKBP10 →	+0.425	+0.314	<.001	.001	3	7
GBM	IKBIP →	+0.835	+0.584	<.001	<.001	3	7
GBM	P4HA1 →	+0.675	+0.441	<.001	<.001	3	7
CCRCC	PLOD1 →	+0.613	+0.529	<.001	.001	3	7
GBM	CRTAP →	+0.654	+0.494	<.001	<.001	3	6
GBM	P4HA2 →	+0.692	+0.491	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,419 associations by consensus.

VKORC1 vs FKBP10 — LSCC

Explore this scatter interactively →