Across TCGA patient cohorts, VIT protein abundance is significantly associated with the RNA expression of many other genes, with 1,844 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible VIT-associated genes across cancer lineages are SLC8A3, SEMA3G, and MEOX2. Each is linked with VIT in more than 1 cancer types. Because this analysis shows association rather than direction, both VIT-to-partner and partner-to-VIT results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VIT→partner) and Y-score (partner→VIT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SLC8A3 →	+0.550	+0.409	<.001	.003	3	2
BRCA	SEMA3G →	+1.403	+1.192	.001	.005	3	2
BRCA	MEOX2 →	+1.176	+1.191	.004	.002	3	2
HNSC	PTPN5 →	+0.526	+0.475	.004	.003	3	2
BRCA	C7 →	+1.871	+1.272	.008	.001	3	2
BRCA	PDE1A →	+0.852	+1.599	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,844 associations by consensus.

Exploration

VIT survival (RNA) · tumor vs normal (RNA) · all VIT data types