Across TCGA patient cohorts, VIT mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VIT-associated genes across cancer lineages are 14-3-3_beta, C-Raf, and Cyclin-B1. Each is linked with VIT in more than 2 cancer types. Because this analysis shows association rather than direction, both VIT-to-partner and partner-to-VIT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VIT→partner) and Y-score (partner→VIT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	14-3-3_beta →	-0.212	-3.000	.045	.036	3	3
UCEC	C-Raf →	+0.132	+1.584	.002	.008	3	3
UCEC	Cyclin-B1 →	+0.437	+1.906	.010	.014	3	3
STAD	eIF4E →	+0.224	+3.000	.016	.036	3	2
SKCM	c-Kit →	-0.597	-3.321	.016	.009	3	2
UCEC	INPP4B →	-0.228	-2.087	.019	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

VIT survival (RNA) · tumor vs normal (RNA) · all VIT data types