VIPR2

Across TCGA patient cohorts, VIPR2 protein abundance is significantly associated with the RNA expression of many other genes, with 266 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VIPR2-associated genes across cancer lineages are RPL14, RNH1, and PSMB5. Each is linked with VIPR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both VIPR2-to-partner and partner-to-VIPR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VIPR2 versus RPL14 in BRCA, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VIPR2→partner) and Y-score (partner→VIPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPL14 →	+0.480	+1.774	.002	.006	3	1
BRCA	RNH1 →	+0.889	+1.839	.004	.005	3	1
GBM	PSMB5 →	-0.508	-1.381	<.001	.002	3	1
GBM	SNTA1 →	+1.681	+1.002	.001	.006	3	1
GBM	FUZ →	+0.724	+1.231	.003	.008	3	1
GBM	SIGLEC5 →	+0.333	+1.681	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 266 associations by consensus.

VIPR2 vs RPL14 — BRCA

Explore this scatter interactively →