VIPR2

Across TCGA patient cohorts, VIPR2 mutation is significantly associated with the RNA expression of many other genes, with 2,076 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VIPR2-associated genes across cancer lineages are RN7SL690P, RNU7-176P, and MYO19. Each is linked with VIPR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both VIPR2-to-partner and partner-to-VIPR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL690P grouped by VIPR2-low versus VIPR2-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VIPR2→partner) and Y-score (partner→VIPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RN7SL690P →	+0.428	+5.352	<.001	.005	3	2
HNSC	RNU7-176P →	+0.874	+5.015	<.001	.009	3	2
UCEC	MYO19 →	+0.424	+2.831	.005	.001	3	2
LIHC	LINC01927 →	+0.170	+4.240	<.001	.008	3	2
UCEC	CEP57L1 →	+0.459	+3.742	<.001	<.001	3	2
UCEC	SF3A3 →	+0.386	+2.855	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,076 associations by consensus.

RN7SL690P by VIPR2 expression — GBM

Explore this box plot interactively →