VIPR1

Across TCGA patient cohorts, VIPR1 mutation is significantly associated with the RNA expression of many other genes, with 1,412 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VIPR1-associated genes across cancer lineages are RN7SKP60, RN7SL201P, and TMEM138. Each is linked with VIPR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both VIPR1-to-partner and partner-to-VIPR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP60 grouped by VIPR1-low versus VIPR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VIPR1→partner) and Y-score (partner→VIPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP60 →	+0.175	+2.257	<.001	.006	3	3
SKCM	RN7SL201P →	+0.141	+3.970	<.001	<.001	3	3
UCEC	TMEM138 →	+0.279	+3.609	.002	.001	3	2
UCEC	OR5J1P →	+0.070	+2.097	<.001	.005	3	2
UCEC	OR52K2 →	+0.065	+2.395	.006	.002	3	2
UCEC	RNA5SP405 →	+0.220	+2.997	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,412 associations by consensus.

RN7SKP60 by VIPR1 expression — UCEC

Explore this box plot interactively →