VIPAS39

Across TCGA patient cohorts, VIPAS39 protein abundance is significantly associated with the RNA expression of many other genes, with 6,595 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VIPAS39-associated genes across cancer lineages are MYC, SEL1L, and TTC8. Each is linked with VIPAS39 in more than 3 cancer types. Because this analysis shows association rather than direction, both VIPAS39-to-partner and partner-to-VIPAS39 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VIPAS39 versus MYC in BRCA, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VIPAS39→partner) and Y-score (partner→VIPAS39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MYC →	-0.786	-0.163	<.001	<.001	3	4
BRCA	SEL1L →	+0.536	+0.184	.006	.004	3	4
UCEC	TTC8 →	+0.570	+0.129	.001	.008	3	4
LSCC	ETV4 →	-1.011	-0.155	<.001	.001	3	4
UCEC	PRR5-ARHGAP8 →	-0.415	-0.098	.005	.002	3	4
LSCC	SPATA7 →	+0.544	+0.219	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,595 associations by consensus.

VIPAS39 vs MYC — BRCA

Explore this scatter interactively →