VIPAS39

Across TCGA patient cohorts, VIPAS39 mutation is significantly associated with the RNA expression of many other genes, with 2,241 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible VIPAS39-associated genes across cancer lineages are LINC02559, VN1R91P, and UBAP1L. Each is linked with VIPAS39 in more than 1 cancer types. Because this analysis shows association rather than direction, both VIPAS39-to-partner and partner-to-VIPAS39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02559 grouped by VIPAS39-low versus VIPAS39-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VIPAS39→partner) and Y-score (partner→VIPAS39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02559 →	+0.814	+4.757	<.001	.004	3	2
BRCA	VN1R91P →	+0.258	+5.473	<.001	.005	3	2
SKCM	UBAP1L →	+0.903	+3.350	<.001	.005	3	2
UCEC	PKN3 →	+0.748	+2.839	<.001	.001	3	2
UCEC	MED27 →	+0.428	+3.892	<.001	<.001	3	2
UCEC	MON1A →	+0.388	+3.595	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,241 associations by consensus.

LINC02559 by VIPAS39 expression — CESC

Explore this box plot interactively →