VIPAS39

Across TCGA cell cohorts, VIPAS39 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,800 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible VIPAS39-associated GO terms across cancer lineages are Protein catabolic process at synapse, Protein catabolic process at postsynapse, and Phosphatidylinositol-3-phosphate biosynthetic process. Each is linked with VIPAS39 in more than 13 cancer types. Because this analysis shows association rather than direction, both VIPAS39-to-partner and partner-to-VIPAS39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein catabolic process at synapse grouped by VIPAS39-low versus VIPAS39-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VIPAS39→partner) and Y-score (partner→VIPAS39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein catabolic process at synapse →	+0.163	+0.892	<.001	<.001	3	14
STOMACH	Protein catabolic process at postsynapse →	+0.163	+0.892	<.001	<.001	3	14
LUNG_SCLC	Phosphatidylinositol-3-phosphate biosynthetic process →	+0.062	+0.527	.005	<.001	3	13
STOMACH	Monoubiquitinated protein deubiquitination →	+0.157	+0.875	<.001	<.001	3	12
KIDNEY	Golgi organization →	+0.061	+0.795	<.001	.003	3	11
URINARY_TRACT	Vesicle tethering →	+0.074	+0.742	.002	.004	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,800 associations by consensus.

Protein catabolic process at synapse by VIPAS39 expression — STOMACH

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