VILL

Across TCGA patient cohorts, VILL RNA expression is significantly associated with the protein abundance of many other proteins, with 11,881 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible VILL-associated proteins across cancer lineages are CAPN5, SSH3, and TMTC3. Each is linked with VILL in more than 4 cancer types. Because this analysis shows association rather than direction, both VILL-to-partner and partner-to-VILL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VILL versus CAPN5 in PDAC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VILL→partner) and Y-score (partner→VILL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CAPN5 →	+0.461	+0.635	<.001	<.001	3	5
LSCC	SSH3 →	+0.355	+0.633	.001	<.001	3	5
PDAC	TMTC3 →	-0.375	-0.918	.001	<.001	3	4
PDAC	CAPNS1 →	+0.332	+0.831	.002	.002	3	4
UCEC	HCLS1 →	+0.405	+0.692	.002	.006	3	4
COAD	IQGAP2 →	+0.453	+0.794	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,881 associations by consensus.

VILL vs CAPN5 — PDAC

Explore this scatter interactively →