Across TCGA cell cohorts, VHLL RNA expression is significantly associated with the go_rna of many other GO terms, with 1,288 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible VHLL-associated GO terms across cancer lineages are Regulation of protein localization to centrosome, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Negative regulation of cytoplasmic pattern recognition receptor signaling pathway. Each is linked with VHLL in more than 6 cancer types. Because this analysis shows association rather than direction, both VHLL-to-partner and partner-to-VHLL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VHLL→partner) and Y-score (partner→VHLL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of protein localization to centrosome →	+0.090	+0.039	<.001	.006	3	7
BLOOD_Leukemia	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.075	+0.060	.002	.006	3	7
OESOPHAGUS	Negative regulation of cytoplasmic pattern recognition receptor signaling pathway →	+0.070	+0.051	.008	.009	3	6
BLOOD_Leukemia	Regulation of aerobic respiration →	-0.045	-0.075	.007	.004	3	5
SKIN	Positive regulation of neurogenesis →	+0.031	+0.042	.003	.008	3	5
OVARY	Response to unfolded protein →	+0.047	+0.042	.006	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,288 associations by consensus.

Exploration

VHLL survival (RNA) · tumor vs normal (RNA) · all VHLL data types