Across TCGA patient cohorts, VGLL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,926 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VGLL3-associated proteins across cancer lineages are CCDC80, AEBP1, and CNN2. Each is linked with VGLL3 in more than 9 cancer types. Because this analysis shows association rather than direction, both VGLL3-to-partner and partner-to-VGLL3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VGLL3→partner) and Y-score (partner→VGLL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCDC80 →	+1.223	+1.279	<.001	<.001	3	10
BRCA	AEBP1 →	+0.926	+0.985	<.001	<.001	3	10
OV	CNN2 →	+1.005	+1.214	<.001	<.001	3	10
GBM	COL3A1 →	+1.086	+0.792	<.001	<.001	3	10
OV	FAP →	+1.378	+1.303	<.001	<.001	3	10
COAD	FKBP7 →	+0.745	+0.836	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,926 associations by consensus.

Exploration

VGLL3 survival (RNA) · tumor vs normal (RNA) · all VGLL3 data types