VGLL1

Across TCGA cell cohorts, VGLL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,236 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible VGLL1-associated GO terms across cancer lineages are Cell-substrate junction assembly, Negative regulation of actin filament polymerization, and Epithelial cell-cell adhesion. Each is linked with VGLL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both VGLL1-to-partner and partner-to-VGLL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate junction assembly grouped by VGLL1-low versus VGLL1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (VGLL1→partner) and Y-score (partner→VGLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cell-substrate junction assembly →	+0.187	+2.744	<.001	<.001	3	10
URINARY_TRACT	Negative regulation of actin filament polymerization →	+0.134	+5.115	<.001	<.001	3	9
BREAST	Epithelial cell-cell adhesion →	+0.237	+3.586	<.001	<.001	3	9
URINARY_TRACT	Regulation of epidermis development →	+0.111	+4.895	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Maintenance of unfolded protein →	+0.140	+2.933	.002	.002	3	9
BREAST	Positive regulation of iron ion transport →	+1.201	+3.260	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,236 associations by consensus.

Cell-substrate junction assembly by VGLL1 expression — STOMACH

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