VGF

Across TCGA patient cohorts, VGF RNA expression is significantly associated with the protein abundance of many other proteins, with 10,200 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible VGF-associated proteins across cancer lineages are NOL6, ATAD2, and CLASP1. Each is linked with VGF in more than 3 cancer types. Because this analysis shows association rather than direction, both VGF-to-partner and partner-to-VGF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VGF versus NOL6 in BRCA, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (VGF→partner) and Y-score (partner→VGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NOL6 →	+0.303	+0.599	<.001	.002	3	4
LSCC	ATAD2 →	+0.573	+0.431	<.001	.001	3	4
LSCC	CLASP1 →	+0.243	+0.269	.002	.001	3	4
LUAD	DLGAP4_T915 →	+0.779	+0.912	<.001	.005	3	4
LUAD	KIF23 →	+0.684	+1.089	.001	.008	3	4
BRCA	UCK2 →	+0.378	+0.642	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,200 associations by consensus.

VGF vs NOL6 — BRCA

Explore this scatter interactively →