VGF

Across TCGA patient cohorts, VGF protein abundance is significantly associated with the RNA expression of many other genes, with 8,050 significant associations in total. GBM shows the largest number of these associations.

The most reproducible VGF-associated genes across cancer lineages are CHGA, SCG3, and RUNDC3A. Each is linked with VGF in more than 2 cancer types. Because this analysis shows association rather than direction, both VGF-to-partner and partner-to-VGF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, VGF versus CHGA in BRCA, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (VGF→partner) and Y-score (partner→VGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CHGA →	+5.533	+1.413	.001	.006	3	3
BRCA	SCG3 →	+4.189	+1.362	<.001	.007	3	3
BRCA	RUNDC3A →	+3.971	+1.357	<.001	.004	3	3
BRCA	GRIA2 →	+4.262	+1.160	<.001	.004	3	3
BRCA	MAPK8IP1 →	+2.654	+1.527	<.001	<.001	3	3
BRCA	SNAP25 →	+4.295	+1.318	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,050 associations by consensus.

VGF vs CHGA — BRCA

Explore this scatter interactively →